a Red Panda awakens from its nap, walks, and naps some more
through bleary eyes,
i look out to see the moon,
then fall back to sleep
My rating: 5 of 5 stars
This is a book about how to keep one’s immune system firing on all cylinders, and it reports on the scientific findings about how a range of lifestyle activities (e.g. exercise, sleep, and nutrition) impact upon the robustness of one’s immune response. The book was exceedingly timely, having been put out last spring in the early days of the pandemic [though I was delinquent in getting to my review until now.]
The book consists of just seven chapters, though they are substantial in length and extent of discussion of the respective topics. The first chapter offers a primer on the immune system, its components, and how it does its crucial job. This chapter also explains how vaccinations work, what autoimmune diseases and allergies are, and what role genetics (nature) and lifestyle / environment (nurture) play in immunity.
Chapter two investigates a range of topics at the nexus of lifecycle and immunity, including: differences between male and female immune responses, pregnancy and immunity, and the effects of aging and menopause on immune system activity.
Chapter three is about our intestinal microbiomes and immunity. If this seems like a strange topic to devote an entire chapter to, you probably haven’t been following the voluminous outpouring of research findings about how our helpful microbiological lifeforms are being shown to have a profound impact on all aspects of human health and well-being from mental health to, well, immune system robustness.
Chapter four explores how immune system activity is compromised by lack of sleep or poor-quality sleep. However, it also looks more broadly at how our immune system responds to the various cycles in which it finds itself — from the daily cycle of days and nights to the yearly seasonal cycle.
Chapter five considers the nexus of mental health and immune response. As was mentioned with respect to the gut, the connections between physiological activity and mental health are becoming ever more apparent – though there remains much to be understood.
The penultimate chapter is about fitness and physical activity and what is know about why exercise is so good for one’s immune response. Of course, there seem to be diminishing marginal returns (less benefit for a given additional workout) and even diminishing returns (negative outcomes) if one goes too crazy with one’s exercise regiment and doesn’t give one’s body adequate amounts of rest.
The final chapter is about the role of nutrition in immune system activity. The approach is very much accord with my own beliefs which are that if one eats right, there is little need for supplements, and no volume of supplements will save you from a poor diet. The emphasis is upon a high-fiber diet rich in plant nutrients and balanced to provide all necessary macro- and micronutrients, while debunking fads and dietary myths. There is discussion of many of the foods that are traditionally associated with immunity (echinacea, elderberry, turmeric, etc.,) and what claims seem to hold and which are unproven.
If you don’t know a lot about the science of healthy lifestyles, this book offers an additional benefit in that it approaches the topic from a quite basic level. That is, it provides a lot of background information that would be useful for a complete neophyte to understand the points about immune activity. So, for example, the author lays out rudimentary explanations of micronutrients or sleep cycles before getting into the relevant information about how these impact on immunity. Of course, the flip side is that for those who have studied this science, it may take some skimming because there is a lot of material that will probably be elementary to those who practice healthy living.
I found this to be an extremely beneficial book. Its focus upon what one can do to improve immune robustness makes it tremendously useful for the average reader. It presents the science without getting too deep in the weeds of detailed physiological activity. I felt the author did an excellent job of walking the line to produce a book that is useful, readable, and digestible.
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I hear voices -- a cold burble of voices -- too dim and distant to extract meaning, too inexplicable not to inject a rationale, or a slate of reasons: -madness -conspiracy -expectation -the impulse toward void filling minds despise quiet, filling it with puzzling prattle, and making any hash of sound into cryptic natter, until sleep descends
In haunted hours, I wilt to sleep, and know that I'll be cursed in dreams. I'll drift upon Stygian streams at speeds between trickle and creep, listening for some distant screams. In haunted hours, I wilt to sleep, and know that I'll be cursed in dreams trapped down below the castle keep, until the King should come to deem me worthy of some healing dreams. In haunted hours, I wilt to sleep, and know that I'll be cursed with dreams, drifting upon Stygian streams.
I lie falling asleep —
purple Rorschach blobs
on the black field of my inner eyelids.
The veneer of reality felt thinner,
but my efforts to poke a finger through
shoved me back into the warm, soft reality of my bed.
[I’d so wanted to “Here’s Johnny!” my way into
an alternate dimension.]
And, once more, I’m a prisoner to reflexes
that snatch away subtle worlds.
Last night the drape was thin and billowy.
Dreams seen through the weep of a willow tree.
Shapes without texture, beings without plights.
A curtain of fog, turning days into nights.
I stood on a corner in the land of nod.
One not crossed in maps of men or gods.
And wondered whether I was found or lost.
Waiting in calm for a morrow tempest-tossed.
But morning light brought me no clarity.
For a long time, the questions of why we sleep and dream remained unanswered — or answered speculatively in ways that proved without merit. One presumes the reasons are potent because there seems to be little evolutionary advantage in spending a third of one’s life unconscious of one’s environs and paralyzed (literally in REM sleep, but for all intents and purposes in NREM sleep as one can’t respond to changes in the environment without some part of one’s brain taking note of said changes.) The good news is that Matthew Walker’s book offers insight into what scientists have learned about why we sleep, why we dream, why we become so dysfunctional without doing both, and what it is about modern life and its technologies that has created an apparent crisis of sleep loss. Walker goes beyond the science to discuss what individuals and institutions can do to reduce the harmful effects of sleep deprivation.
The downside of this book is that it’s a bit alarmist, and in contrast to many books of this nature one doesn’t get a good indication of the quality of studies reported. Some pretty brazen claims are made and the reader doesn’t necessarily know if they are preliminary and unvalidated or if they are well established. Here, I’m speaking about the studies that try to isolate out the effect of sleep loss versus all other factors (which is a notoriously messy affair,) and not so much studies that report on the physiological effects of sleep and sleep loss (which I see less reason to not take at face value.) At any rate, any reader who doesn’t fall asleep as soon as his head hits the pillow and sleep straight through 7 hours and fifty-five minutes — waking 5 minutes before the alarm — is likely to feel doomed if they take this book too seriously. And if you ever engaged in shift-work (as I have) or had an intense travel schedule, you are likely to feel that your life is permanently and irretrievably wrecked.
I know this is a book on sleep, but I think it went a little too far in marginalizing all other elements of health and well-being. Walker said that he used to tell people that sleep, nutrition, and exercise were the trifecta of good health, but he ultimately concluded that sleep was more important because diet and exercise were adversely impacted by sleep loss. I don’t disagree that diet and exercise are harmed by sleep loss, but – of course – sleep quality is harmed by lack of proper diet and exercise as well. The author later discusses research confirming this two-way street. I, therefore, have no idea why he changed his initial balanced and reasonable view with one that suggests sleep is the 800-pound gorilla of health and well-being.
The book’s 16 chapters are divided into four parts. Part I (Ch. 1 – 5) lays out what sleep is, how rhythms of sleep are established / disrupted, how much sleep one needs, and how one’s sleep needs change throughout the course of one’s life. Part II (Ch. 6 – 8) explores the benefits of sleeping as well as describing the nature of the damage caused by lack of sufficient sleep. Part III (Ch. 9 – 11) shifts the focus to dreams, and delves into what they appear to do for us. The final part (Ch. 12 – 16) investigates the many ways in which modern life disrupts sleep from blue light in LED’s to arbitrary school and work schedules to cures that are worse than the ill (i.e. sleeping pills.)
There is an appendix that summarizes twelve key changes that an individual can make to get more and better sleep. There are graphics throughout the book, mostly line-drawn graphs to provide visual clarity of the ideas under discussion.
I found this book interesting and informative. I would recommend it for anyone interested in the science of sleep or how they might sleep better, with the exception of anyone who has anxiety about the state of his or her health and well-being. While I understand that Dr. Walker wants to drive changes regarding views and policies that have been wrong-headed or deleterious regarding sleep, I feel he went too far toward suggesting the sky is falling for anyone who gets less than a perfect night’s sleep every night of his life.
like snow accumulates
what world is this
where doors are portals
processing drops to
is more sedating
the world blurs
slows to zero
This month, I skipped two consecutive nights sleep to explore the effect of sleep deprivation on consciousness. Forty-eight hours without sleep may not sound like much. A two-day fast will make you feel hungry, but is hardly a challenge for the body of a healthy individual. Of course, most people could go a few weeks without food as long as they could reduce physical activity.
Sleep may be more closely analogized to water. It’s often said that a person can go a week without water, but some people have succumbed after three or four days. The world record for consecutive time without sleep is 11 days and 25 minutes, set by Randy Gardner in 1964, but most people will experience some severe challenges after a few days, and after even one day it’s not safe to do many fairly rudimentary life tasks (i.e. driving, making important life decisions, doing any work that requires concentration.) [Note: Gardener points out that it was day three when he started to feel nausea and the challenge started to feel daunting.] My choice of two days was largely influenced by the limit of how long I could go without being productive. Into the second day, maintaining the level of concentration necessary to edit or write finished product becomes almost impossible for me and it rapidly gets worse, and I certainly couldn’t safely drive my scooter.
Unfortunately, I’m no stranger to sleep deprivation, though it was mostly in my youth. That makes it sound like I was a party-animal, though I wasn’t (certainly not by the standards of true party-animals.) In truth, in the military I started out working twelve hour night shifts, and I found I could rarely sleep more than four-ish hours per day. Later (still in the military) I worked days at a base in Georgia, but I would frequently (once, sometimes twice, a week) travel from Warner Robins to Atlanta after work for martial arts classes. Often, hanging out with friends after night classes, I would return to base in the wee morning hours and — on a number of occasions — missed a night’s sleep because I didn’t have enough time to get in even a solid two hours before I had to be ready for the 6am shift change. (Note: I’m a groggy napper. While some people swear by naps, I find they tend to make me even more fuzzy-headed — especially if I’m in need of more sleep than I have time to get.) [FYI: My personal record for sleeplessness is a little longer than I did this time — 55 hours-ish. It was also when I was a young man in the military.]
Where sleep is very different (from food or water) is that until recently we didn’t have the foggiest idea why we needed it. Biologists could tell us why we need air, water, and food decades ago, but no one knew why we needed sleep — only that bad stuff happened in pretty soon when we didn’t get sleep. I was under the impression that we still didn’t know (and it’s probably true that we don’t yet have a complete picture.) However, I started reading Matthew Walker’s Why We Sleep, and he suggests that it’s not that we don’t know why we sleep, but rather that it’s not the simple one-to-one cause-and-effect relationship that sleep researchers had hoped to discover as a Holy Grail of sleep causation. Walker says we know a great deal about why we sleep, it’s just that there are a large number of aspects of our body’s operation that hinge on sleep. In other words, it’s a complex many-to-one relationship between causes and sleep. [Another reason I kept a limit on this experience was the book’s discussion of how many adverse impacts sleep disruption can have, and — more importantly — how long-lived the effects of sleep deprivation can be.]
There were a number of ways the sleep deprivation was felt. Of course, the predominant sensation was just an incredible pressure to go to sleep, i.e. heavy eyelids, mental drift, and “head-nodding” micro-sleep. There’s a great deal of discussion about how memory degrades under sleep deprivation, because sleep / dreams seem to be heavily involved in the memory process. I didn’t notice any memory defects [any more than I might normally have.] However, I readily noticed a decline in concentration and focus. After a day without sleep, I found that my ease of proof-reading / editing was significantly reduced even when I did it during those times when I was most awake and didn’t really feel particularly sleepy. A one-hour task would take decidedly more than that, and I recognized that I shouldn’t do any finished work because even if I took twice as long I’d likely still miss mistakes. Toward the end of the second day, I had trouble even following a sitcom story on the television (thought that was at the point in circadian rhythms when I was most desirous of sleep.)
The other mental effect I noticed was a mild altered sensory perception. This was nothing like the psilocybin tea altered perception. The first thing I notice was a little bit of movement in my visual field if I zoned out while staring at at the floor (and zoning out happens much more than it ordinarily would after a good night’s sleep.) Again, this wasn’t vivid like the shrub that sinuously wound in a serpentine fashion when I tried psilocybin tea. Rather it was just a kind of tiny “stretching” of floor surface when I looked down. You’d have to pay attention for it and might rub one’s eye to try to get rid of it. The second thing I noticed was some auditory strangeness. I heard a barking dog in a passing car, and it was as if that one sound was turned up even as the car was getting further away (or perhaps like the other sounds were turned down. All I know is that the barking of the dog took a dominant position in my auditory awareness. I wasn’t anything wild, like the dog talking to me. I suspect that would take another couple days of complete sleep deprivation. And I have no particular anxiety about dogs or barking noises.)
Physically, there were a few other noteworthy effects. First, I found myself getting chilly even with no AC on and even after I turned the fan off. What’s important to note is that I tend to run hot, and in Bangalore if I feel chilly it probably means I have the flu. I’ve known for a long time that thermoregulation is disrupted during sleep. (This is why one may go to bed comfortable and wake up in a sweat puddle, or — for some, I suppose — go to bed comfortable and wake up freezing. It’s not necessarily a change in the room’s temperature, it’s that your body isn’t so much adjusting the difference between room temperature and body temperature anymore.) I found the chill interesting. The fact that I wasn’t sleeping seemed to me should have meant that reduced thermoregulation should be irrelevant. However, after the fact I learned (again in the Walker book) that body temperature changes with one’s bodily rhythms, and that is presumably what I was feeling.
Second, I noticed a very mild rumbly-tummy effect. I didn’t realize how much sleep problems can be tied into eating problems until reading about it, but I have noticed in the past that my stomach gets a sensation that is akin to being hungry if I’m on no sleep — even if I’ve not been without food (at least not more than I normally would be through the night.)
Those were the most noticeable effects. I can see why some people have had similar experiences while severely sleep deprived as during mystical experiences of other cause (e.g. hallucinations from consuming substances, severe fasting, etc.) Still, for me, the long and short of it was that sleep deprivation had (in contrast to the the other practices I’ve done in this series) a clearly negative impact on the performance of body and mind. From difficulty concentrating to a slow time when running, my body was hindered by lack of sleep. Sleep deprivation diminished my mental and physical competence with no offsetting benefit that I could determine (other than assuaging my curiosity.)
Next month’s post on experiencing altered states of consciousness will be on a mystery topic. [Which may or may not be my way of admitting I’m not sure what I’m going to do yet.]