Category Archives: Physiology

BOOK REVIEW: Body Am I by Moheb Costandi

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Body Am I: The New Science of Self-ConsciousnessBody Am I: The New Science of Self-Consciousness by Moheb Costandi
My rating: 5 of 5 stars

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In this book you’ll learn about: a man who wanted a perfectly healthy leg amputated, a fisherman who felt like his hands were crab claws, a woman who felt she wasn’t responsible for the actions of her hand, various people who’ve experienced “Alice in Wonderland Syndrome” [i.e. feeling one has shrunk or stretched,] and about many other issues stemming from the body’s sensory and motor integration with what we think of as the mind. For most of us, the most powerful take-away to be gained from this book is just how wonderful and awe-worthy it is that we have bodies that are so well integrated and coordinated that we can go about life engaging in all sorts of fascinating and productive activities.

While this isn’t the only book that addresses this subject, I think it’s a topic worth learning more about and reflecting upon in depth. We can get so out of touch with the fact that our body is integrated with our mental and sensory experiences that we take “brain in a vat” scenarios as a given for the near future, as if one is the sum of one’s neuronal connections. This book will disabuse one this notion. In fact, the final chapter (Ch. 10) questions the proposition that copying consciousness is a matter of mastering such neuronal mapping. It’s easy to miss how much of our emotional experience is rooted in what’s happening in our guts and heart, and how much all the non-central nervous system parts of the body play in our conscious experience of the world.

I learned a great deal from this book and would highly recommend it.

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BOOK REVIEW: Introducing Epigenetics by Cath Ennis

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Introducing Epigenetics: A Graphic Guide (Introducing...)Introducing Epigenetics: A Graphic Guide by Cath Ennis
My rating: 4 of 5 stars

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I’m old enough to remember when the human gene sequence was first being decoded, and there was a widespread belief that it was going to end genetic diseases in one fell swoop. It didn’t do that, and – in fact – seemed to result in whole new levels of confusion. It’s fascinating to me that now Epigenetics, a subject that grew out of that confusion, is also being seen as the ticket to ending disease. Epigenetics investigates what traits are expressed and why, given that a specific gene sequence has a vast array of potential for various traits to be (or not to be) expressed.

For those familiar with this series (the “A Graphic Guide” series,) this book is more difficult to digest than most titles, certainly than any of the several others that I’ve read. To be fair, the subject matter is more technical than most, leading to it being more jargon- and acronym-intensive. In addition, the subject isn’t cut up into as small of pieces as most of the books. This one has far fewer and longer chapters than the others that I’ve read.

That said, while it reads technically for the general reader, there are a few concepts (methylation, demethylation, and histone modification) that are frequently revisited throughout the book, and so one can get a basic grasp of those concepts. The book also explores some issues that are more readily understood by the lay reader, such as: nature v. nurture in gene expression, the role of twin studies, and how pseudo-scientific individuals and organizations have made fraudulent claims involving Epigenetics.

If you want to learn about the fundamentals of Epigenetics, you may want to look into this book — but keep in mind that it’s not a smooth read.

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BOOK REVIEW: The Exquisite Machine by Sian E. Harding

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The Exquisite Machine: The New Science of the HeartThe Exquisite Machine: The New Science of the Heart by Sian E. Harding
My rating: 5 of 5 stars

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Release date: September 20, 2022

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In this book, a renowned heart researcher presents an overview of what we know (and don’t know) about the human heart: i.e. what can go wrong with it and why, how [and to what degree] it fixes itself, and what modern medicine can do to treat or replace a damaged heart. I learned the most from the middle of the book – i.e. chapters five through seven. Chapter five explores plasticity in the heart, plasticity is a concept that most people associate with the brain and its ability to rewire itself to contend with damage or changing needs. The other two chapters look at how the heart can be damaged, specifically as a result of emotional experience. A “broken heart” isn’t necessarily a misnomer.

Chapter four is also intriguing but takes the win for “which one of these things is not like the others.” It deals with big data, though not in a general sense but rather as it applies to gaining a better understanding of the heart. This chapter discusses a common challenge of medical research: that it’s hard to come up with large enough study groups of patients with close enough to the same problem to draw solid conclusions. Four also discusses the potential of the vast amount of data that exists, e.g. Fitbit heart rate figures.

The last couple chapters deal largely with the future of heart repair through genetic / biological means (as opposed to via mechanical hearts and technologies, which are dealt with in Chapter nine.) This is where the book gets to be a challenging read for a readership of non-experts. It gets technical and jargon- / acronym-heavy.

The heart is an astounding entity, relentlessly at work, rarely giving up despite regularly being subjected to intense shocks, an organ tied to our whole being in a way that humans have always felt – if only just begun to understand. If you’re interested in learning more about this magnificent organ, check this book out.

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BOOK REVIEW: Training and Conditioning for MMA ed. by Dias / Oliveira / Brauer & Pashkin

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Training and Conditioning for MMA: Programming of ChampionsTraining and Conditioning for MMA: Programming of Champions by Stéfane Beloni Correa Dielle Dias
My rating: 5 of 5 stars

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Release Date: September 15, 2022 [It may already be out in some formats and markets]

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This book provides an overview of fitness building for Mixed Martial Arts athletes. It covers program design, athletic assessment, nutrition, exercises and conditioning practices, and injury prevention methods. On the positive side, it’s not only comprehensive, but – also – presents some of the best and latest methods in combative sports training based on sound scientific research. On the other hand, the book does assume a certain level of understanding of sports science, and it gets pretty deep in the weeds with respect to technical detail and to scientific and specialty jargon. If one doesn’t have such background, one may find some of the content (particularly the early chapters) a bit daunting. That said, it offers an excellent reference for those who are interested in methods and sports science not just for MMA, but for combative sports, in general.

The book uses color photographs throughout. I found the photos to be clear, well-sized, and well-lit. While there is definitely an attempt to keep the number of photos to a reasonable level, they do offer multiple angles where necessary and – generally – give enough pictures to make the action clear. There are also tables after each of the methods sections to give a handy summary of sets, reps, and scheduling suggestions for various exercises. In the early chapters, the ones that convey more technical content, there’re charts, graphs, and diagrams as needed. There’s an extensive bibliography, though it should be noted many if not most of the references are not in English. (The team of editors and contributors is large and international.)

This book offers an excellent reference for coaches, trainers, and athletes. While it does get quite technical, it’s great that it offers insight into cutting edge science and training methods.


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BOOK REVIEW: The Physiology of Yoga by Andrew McGonigle & Matthew Huy

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The Physiology of YogaThe Physiology of Yoga by Andrew McGonigle
My rating: 5 of 5 stars

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This is a much-needed book for two reasons. First, while there are a number of fine books on anatomy as it applies to yoga, such books focus on the musculoskeletal system, occasionally venturing into the respiratory system – re: pranayama (breathwork.) However, yoga anatomy books rarely giving an overview of the workings of the body as a whole or describe how yoga influences and is influenced by other bodily systems. This book systematically reviews not only the muscles, bones, and lungs, but offers insight into the less familiar systems, such as the lymphatic, immune, and endocrine systems. Unless you want to know more about yoga and the integumentary system (skin, hair, and nails,) this book has got you covered. The book does an excellent job of avoiding muddling science with mythological beliefs about the body, a common sin among yoga books.

Second, there are many physiology misunderstandings and mistakes that are widespread and have come to be repeatedly parroted by new generations of teachers. These range from ideas that are unsupported by scientific evidence to those that are completely in conflict with well-understood science. This book has text boxes throughout that investigate widely taught physiology myths (e.g. twists detox the liver, shoulder stands stimulate the thyroid & pineal glands, kapalbhati (forced exhalation breathing) stops the aging process, heavy sweating detoxifies the body, and various claims about specific asana / practices curing specific ailments.) These boxes review what studies have been done on each claim, and (in the absence of scientific literature) it discusses whether claims make any sense in light of well-established physiological science.

The book is clear and easy to read, and has well-drawn anatomical drawings and diagrams to help communicate the workings of the body. It also has an extensive bibliography of works referenced.

The book wasn’t perfect. I thought the last chapter, which is a collection of yoga sequences, was out of place and unnecessary, given the objectives of this book. I suspect its inclusion was solely to remind readers flipping through the book that they were reading a book about yoga as well as physiology. (The graphics and headings don’t necessarily scream yoga.) However, I think this could have been more relevantly and effectively by including more graphics throughout that show individuals engaged in yogic practices / asana, or – alternatively – focusing on the physiological aspects of the practices and sequences in the last chapter. There was also a place or two where I wasn’t sure what the authors were saying, not because they didn’t write in a clear and readable style or because what they were saying wholly conflicted with what I understood to be true, but just because there was enough ambiguity that I was left puzzled.

Overall, I’d recommend this book for yoga teachers and practitioners looking to expand their understanding of the workings of the human body, and to liberate themselves from some misinformation that has gained a following.


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BOOK REVIEW: Life at the Extremes by Frances Ashcroft

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Life at the ExtremesLife at the Extremes by Frances Ashcroft
My rating: 5 of 5 stars

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Anyone interested in the limits of human physiology will find this book fascinating. Technically, its subject matter is broader than that, considering the environmental limits of living creatures, generally. However, all but the last chapter focuses on how humans react to (and adapt to) extreme conditions. Chapters one through six explore the challenges and limitations of humans under extreme conditions of elevation (ch. 1,) of pressure [underwater] (ch. 2,) of heat (ch. 3,) of cold (ch. 4,) of intense physical activity [running-centric, but deals with strength and power as well] (ch. 5,) and in space (ch. 6.) Then, each chapter reflects upon examples of species that are extremely well-adapted to said conditions, and why. (e.g. After learning about how and why humans have to acclimate to survive high elevation treks, one learns about the bar-headed goose, a bird that can go from sea level to flying over Everest – all in the same day.)

The final chapter (ch. 7) is a bit different in that it discusses extremophiles, creatures that can survive in a wide range of conditions (e.g. acidity, temperature, lack of moisture, lack of oxygen, etc.) that would be certain death not only for humans but for any animals. Most of the species discussed are either single-celled creatures or tiny multi-cellular life (e.g. Tardigrades.) With respect to humans, there is a discussion of the limits and present understanding of suspended animation.

This book offers an intriguing look at life at the extremes. While written by a Professor of Physiology, it’s highly readable for a general audience. It mixes narrative examples in with the discussion of physiology to make the material approachable and engaging. I’d highly recommend this book.


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BOOK REVIEW: Drunk Flies and Stoned Dolphins by Oné R. Pagán

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Drunk Flies and Stoned Dolphins: A Trip Through the World of Animal IntoxicationDrunk Flies and Stoned Dolphins: A Trip Through the World of Animal Intoxication by Oné R. Pagán
My rating: 5 of 5 stars

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Humanity’s proclivity to think ourselves above nature has led us to miss the fact that we aren’t the only intelligent creatures and that we share more in common with the rest of the animal kingdom than – perhaps – we’d like to think. Science’s recognition of this truth has spawned a vast collection of books on animal (and, for that matter, plant) intelligence as well as the other traits we share in common with different species. This book carves out an interesting niche in this literature by discussing how other creatures use psychoactive substances (i.e. what we think of as “drugs and alcohol.”) While people tend to think that we are alone not only with respect to intelligence, but also with respect to our vices, it turns out this doesn’t seem to be the case. Of course, there’s a lot we don’t know about dolphins that play with blowfish or monkeys on magic mushrooms – e.g. what their internal experience of the substance is like, and to what degree consumption is purposeful versus accidental, but there is an increasing number of studies that suggest other species use drugs, and like it. The book also delves into the role plants play, particularly in producing substances that have psychoactive effects.

This book is humorous (the material is certainly there) and intriguing. It’s an easy pop science read, and avoids becoming too bogged down in the minutiae of biochemistry. That said, it does include graphics, such as chemical diagrams of psychoactive molecules, and does have to dip its toe into concepts of biology and chemistry. If you find the topic intriguing, you should give it a read.

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BOOK REVIEW: Yoga Anatomy, 3rd Ed. by Leslie Kaminoff and Amy Matthews

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Yoga AnatomyYoga Anatomy by Leslie Kaminoff
My rating: 5 of 5 stars

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This book has several competitors, and so this review will focus on a few of the features that I believe make it one of the best books on yoga anatomy, and the most appropriate for many users. To clarify, H. David Coulter’s “Anatomy of Hatha Yoga” has some advantages over this book, but Coulter’s book is also denser and will send neophyte readers to the glossary / internet / library much more often. On the other hand, some of the other yoga anatomy books fixate entirely on postural yoga and treat it entirely as a matter of skeletal alignment and muscular engagement. While a lot of this book (and any such book, really) focuses on skeletal alignment and muscular engagement, I appreciated the books exploration of breath and the nervous system – topics that are often neglected. In short, this book offers a mix of reader-friendliness and detail that makes it at once approachable and tremendously informative.

One important feature of this book is that it avoids the dogmatism of some yoga texts, encouraging experimentation and recognizing that a one-size-fits-all approach to bodies is bound to fail. This can best be seen in the “Cueing Callout” boxes that explore the pithy adjustment directives for which yoga teachers are famous (and often satirized,) advice that is often misunderstood in ways detrimental to a student’s progress.

A second key feature involves keeping anatomy and physiology distinct from the folk science of yoga / ayurveda. While Kaminoff and Matthews do refer to ideas like prana and apana, they do so in a broad, conceptual way that doesn’t conflate said ideas with science. A common problem in yoga texts is conflation of science with folk science such that confused readers are left with a muddle of puzzle pieces that don’t belong to the same puzzle.

Finally, as one who’s found pranayama (breathwork) to be one of the most profoundly transformative elements of a yoga practice, I appreciated that the book not only had a chapter on breath dynamics, but that all the posture discussions included a “breath inquiry” section that encouraged readers to reflect upon the effect of the posture on breathing, as well as suggesting ways in which a practitioner might experiment to improve one’s breathing.

The only criticism I have is that many of the text-boxes in the early chapters seemed to contain random information that could have been incorporated into the text, into footnotes, or edited out altogether. [In contrast to the aforementioned “Cueing Callout” boxes that had a clear and distinct purpose.] If you’re a yoga teacher or dedicated practitioner without a deep scientific background, you’d be hard-pressed to do better than this book for learning about the anatomy of yoga.


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BOOK REVIEW: BrainComix by Jean-François Marmion

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BraincomixBraincomix by Jean-François Marmion
My rating: 5 of 5 stars

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This nonfiction graphic novel surveys the brain and what it does, including: sensory processing, memory, attention, unconscious activities, learning, language, emotional experience, etc. It also reviews some of the more intriguing brain disorders (e.g. synesthesia, apraxias, phantom limb syndrome, etc.) and what they tell us about the nature of the mind.

If you’re looking for a soup-to-nuts overview of the brain that covers the gist without getting in too deep, and which is quick and easy, this book is hard to beat. If you have read much about neuroscience, you probably won’t be introduced to anything new. The book employs the usual suspects of pop-sci neuroscience and cognitive psychology: Phineas Gage (i.e. rebar through the brain guy,) H.M. (i.e. couldn’t form new memories after brain surgery guy,) the rubber hand experiment, the gorilla basketball experiment, etc. However, because it’s such a quick and light read, it’s not much of an investment to review these topics, and – who knows – maybe you’ll retain more due to the graphics.

The premise is a simple one, the brain is being interviewed for a Larry King-style talk show that at times becomes a Jerry Springer-style show as “characters” (e.g. a neuron, a homunculus, the conscious mind, etc.) charge the stage to get in their two cents. This might not be the most creative or clever approach that could’ve been taken, but it also doesn’t distract from the objective of teaching about the brain – as a more intense plot might have done. The art is crudely drawn, though I suspect this is on purpose to make clear this is not a textbook, but rather a pop-sci book.

If you are looking for an introduction to the brain, you should check this book out. (Also, if you’re looking to review, quickly and concisely, you might find it of value as well.)

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BOOK REVIEW: Immunity by Jenna Macciochi

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Immunity: The Science of Staying Well—The Definitive Guide to Caring for Your Immune SystemImmunity: The Science of Staying Well—The Definitive Guide to Caring for Your Immune System by Jenna Macciochi
My rating: 5 of 5 stars

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This is a book about how to keep one’s immune system firing on all cylinders, and it reports on the scientific findings about how a range of lifestyle activities (e.g. exercise, sleep, and nutrition) impact upon the robustness of one’s immune response. The book was exceedingly timely, having been put out last spring in the early days of the pandemic [though I was delinquent in getting to my review until now.]

The book consists of just seven chapters, though they are substantial in length and extent of discussion of the respective topics. The first chapter offers a primer on the immune system, its components, and how it does its crucial job. This chapter also explains how vaccinations work, what autoimmune diseases and allergies are, and what role genetics (nature) and lifestyle / environment (nurture) play in immunity.

Chapter two investigates a range of topics at the nexus of lifecycle and immunity, including: differences between male and female immune responses, pregnancy and immunity, and the effects of aging and menopause on immune system activity.

Chapter three is about our intestinal microbiomes and immunity. If this seems like a strange topic to devote an entire chapter to, you probably haven’t been following the voluminous outpouring of research findings about how our helpful microbiological lifeforms are being shown to have a profound impact on all aspects of human health and well-being from mental health to, well, immune system robustness.

Chapter four explores how immune system activity is compromised by lack of sleep or poor-quality sleep. However, it also looks more broadly at how our immune system responds to the various cycles in which it finds itself — from the daily cycle of days and nights to the yearly seasonal cycle.

Chapter five considers the nexus of mental health and immune response. As was mentioned with respect to the gut, the connections between physiological activity and mental health are becoming ever more apparent – though there remains much to be understood.

The penultimate chapter is about fitness and physical activity and what is know about why exercise is so good for one’s immune response. Of course, there seem to be diminishing marginal returns (less benefit for a given additional workout) and even diminishing returns (negative outcomes) if one goes too crazy with one’s exercise regiment and doesn’t give one’s body adequate amounts of rest.

The final chapter is about the role of nutrition in immune system activity. The approach is very much accord with my own beliefs which are that if one eats right, there is little need for supplements, and no volume of supplements will save you from a poor diet. The emphasis is upon a high-fiber diet rich in plant nutrients and balanced to provide all necessary macro- and micronutrients, while debunking fads and dietary myths. There is discussion of many of the foods that are traditionally associated with immunity (echinacea, elderberry, turmeric, etc.,) and what claims seem to hold and which are unproven.

If you don’t know a lot about the science of healthy lifestyles, this book offers an additional benefit in that it approaches the topic from a quite basic level. That is, it provides a lot of background information that would be useful for a complete neophyte to understand the points about immune activity. So, for example, the author lays out rudimentary explanations of micronutrients or sleep cycles before getting into the relevant information about how these impact on immunity. Of course, the flip side is that for those who have studied this science, it may take some skimming because there is a lot of material that will probably be elementary to those who practice healthy living.

I found this to be an extremely beneficial book. Its focus upon what one can do to improve immune robustness makes it tremendously useful for the average reader. It presents the science without getting too deep in the weeds of detailed physiological activity. I felt the author did an excellent job of walking the line to produce a book that is useful, readable, and digestible.

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